Why the study?
An inferential analysis of technical success and serious adverse events in a large series of fetal aortic valvuloplasties had not been reported.
What factors are associated with technical success and serious adverse events in fetal aortic valvuloplasty?
Population
163 patients (165 attempted FAVs) with severe aortic valve stenosis and evolving hypoplastic left heart syndrome
Comparison
Factors associated with technical success and serious adverse events during attempted FAV
Design
Retrospective single-center cohort analysis
Authors
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Smaller fetal left hearts linked to lower FAV success and more SAEs; leaves open refined selection criteria pending prospective validation.
What factors are associated with technical success and serious adverse events in fetal aortic valvuloplasty?
Technical success of fetal aortic valvuloplasty has improved over a 20-year period, though serious adverse events remain common and are strongly associated with smaller left heart size and longer procedure times.
Callahan et al. (2024) studied this question.
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