Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 1, 2018Ultrasound in Obstetrics and GynecologyOpen Access

Intervention for fetal critical aortic stenosis: first step in a metamorphosis?

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does fetal aortic valvuloplasty improve the rate of biventricular outcome in fetuses with critical aortic stenosis?

Population

Fetuses with critical aortic stenosis

Comparison

Fetal aortic valvuloplasty via percutaneous… vs Natural history (no in-utero intervention)

Design

Editorial

Authors

EJEdgar JaeggiRCRajiv Chaturvedi

Discussion

Loading...

Member takes

Overview

FAV for critical aortic stenosis may improve fetal outcomes; leaves open need for prospective trials to guide selection and confirm benefit.

Structured PICO

Does fetal aortic valvuloplasty improve the rate of biventricular outcome in fetuses with critical aortic stenosis?

P
Population
Fetuses with critical aortic stenosis
I
Intervention
Fetal aortic valvuloplasty (FAV) via percutaneous ultrasound-guided balloon dilation
C
Comparator
Natural history (no in-utero intervention)
O
Outcome
Biventricular (BV) outcome/repair

Fetal aortic valvuloplasty can improve the likelihood of achieving a biventricular circulation in critical aortic stenosis, though success heavily depends on institutional experience and complex postnatal management.

Limitations

  • Lack of adjustments for gestational age or fetal weight in predictive models
  • Beneficial effects of FAV may be masked by the complexity of postnatal management

Cite This Study

Jaeggi et al. (2018) studied this question.

synapsesocial.com/papers/6a71f7485d37378ac1deeef1https://doi.org/10.1002/uog.19159
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Fetal hemodynamic response to aortic valvuloplasty and postnatal outcome: a European multicenter study2017 · 70 citations
  2. 2Natural history of 107 cases of fetal aortic stenosis from a European multicenter retrospective study2016 · 87 citations
  3. 3Predictors of Technical Success and Postnatal Biventricular Outcome After In Utero Aortic Valvuloplasty for Aortic Stenosis With Evolving Hypoplastic Left Heart Syndrome2009 · 313 citations
  4. 4Intrauterine aortic valvuloplasty in fetuses with critical aortic stenosis: experience and results of 24 procedures2011 · 137 citations
  5. 5Low rate of prenatal diagnosis among neonates with critical aortic stenosis: insight into the natural history <i>in utero</i>2014 · 49 citations