Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
November 2, 2021Ultrasound in Obstetrics and GynecologyOpen Access

Postnatal circulation in patients with aortic stenosis undergoing fetal aortic valvuloplasty: systematic review and meta‐analysis

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Fetal aortic valvuloplasty (FAV) aims to preserve biventricular circulation in critical fetal aortic stenosis, but it remains unclear how many patients achieve this postnatal outcome.

Does fetal aortic valvuloplasty improve the rate of biventricular circulation in fetuses with critical aortic stenosis?

Design

Systematic review and meta-analysis

Follow-up

Median follow-up per study from 12 months to 13.2 years

Authors

CVCarina Nina VorisekDZDavid ZurakowskiATArturo Tamayo

Discussion

Loading...

Member takes

Overview

Biventricular circulation achieved in ~46% of liveborn FAV cases; leaves open optimal selection criteria for prospective trials.

Structured PICO

Does fetal aortic valvuloplasty improve the rate of biventricular circulation in fetuses with critical aortic stenosis?

P
Population
266 fetuses with critical fetal aortic stenosis (AS) from 7 studies. Hydrops was present in 11% of patients.
I
Intervention
Fetal aortic valvuloplasty (FAV)
O
Outcome
Type of postnatal circulation (biventricular vs univentricular)hard clinical

Fetal aortic valvuloplasty achieves biventricular circulation in approximately 46% of liveborn patients with critical aortic stenosis, though the lack of randomized data limits definitive conclusions regarding its true benefit.

Limitations

  • lack of randomized clinical trials

Cite This Study

Vorisek et al. (2021) studied this question.

synapsesocial.com/papers/6a715bf0febe604dd70a0823https://doi.org/10.1002/uog.24807
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Natural history of 107 cases of fetal aortic stenosis from a European multicenter retrospective study2016 · 87 citations
  2. 2Intrauterine aortic valvuloplasty in fetuses with critical aortic stenosis: experience and results of 24 procedures2011 · 137 citations
  3. 3Predictors of Technical Success and Postnatal Biventricular Outcome After In Utero Aortic Valvuloplasty for Aortic Stenosis With Evolving Hypoplastic Left Heart Syndrome2009 · 313 citations
  4. 4Outcomes of hypoplastic left heart syndrome and fetal aortic valvuloplasty in a country with suboptimal postnatal management2019 · 16 citations
  5. 5Natural history and outcome of aortic stenosis diagnosed prenatally.1997 · 190 citations