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November 27, 2009Fetal Diagnosis and Therapy

Balloon Dilatation of the Aortic Valve in the Fetus

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Why the study?

Does balloon dilatation of the aortic valve in utero improve outcomes in a fetus with critical aortic stenosis?

Population

1 fetus with critical aortic stenosis diagnosed in utero at 27 weeks' gestation

Design

Case_report

Follow-up

Until first day of life

Authors

LLLílian Maria LopesPolytechnic Institute of Viana do CasteloSCSang ChoonFetal Medicine FoundationLKLuíz Junya KajitaUniversidade de São Paulo

Discussion

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Implication

In utero aortic balloon dilatation did not prevent neonatal death in this case; leaves open whether it improves outcomes in critical aortic stenosis.

Structured PICO

Does balloon dilatation of the aortic valve in utero improve outcomes in a fetus with critical aortic stenosis?

P
Population
1 fetus with critical aortic stenosis diagnosed in utero at 27 weeks' gestation
I
Intervention
Balloon dilatation of the aortic valve in utero
O
Outcome
Survival and progression of endocardial fibroelastosishard clinical

In utero balloon dilatation for critical aortic stenosis did not prevent the progression of endocardial fibroelastosis or neonatal death in this case.

Cite This Study

Lopes et al. (2009) studied this question.

synapsesocial.com/papers/6a715bf2febe604dd70a0825https://doi.org/10.1159/000264318
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Balloon dilatation of the aortic valve in the fetus: a report of two cases.1991 · 251 citations
  2. 2Balloon valvuloplasty for critical aortic stenosis in a fetus: a case report2013 · 9 citations
  3. 3Prenatal therapy of non‐immunologic hydrops fetalis caused by severe aortic stenosis2000 · 22 citations
  4. 4Prenatal aortic valvuloplasty as a definite treatment in fetuses with critical aortic stenosis, severe mitral regurgitation and giant left atrium: a report of two cases with medium-term follow-up2022 · 2 citations
  5. 5Balloon dilatation (valvoplasty) as first line treatment for severe stenosis of the aortic valve in early infancy: medium term results and determinants of survival.1993 · 47 citations