Key result
Administration of aspirin or aspirin-like drugs prevented thrombosis resulting in hemiparesis following carotid reconstructive surgery compared to historical controls (0 vs 5 patients).
Why the study?
Does administration of aspirin or aspirin-like drugs reduce thrombosis and neurological complications in patients undergoing internal carotid artery endarterectomy?
Population
Patients undergoing internal carotid artery (ICA) endarterectomy for symptomatic cerebral occlusive disease
Comparison
Aspirin (or aspirin-like) drugs vs Comparable group from the previous year in whom…
Design
Cohort
Authors
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May reduce neurological complications after carotid surgery; hypothesis-generating and requires randomized confirmation.
Does administration of aspirin or aspirin-like drugs reduce thrombosis and neurological complications in patients undergoing internal carotid artery endarterectomy?
The use of aspirin or aspirin-like drugs may reduce the incidence of neurological complications and thrombosis following carotid reconstructive surgery.
Edwards et al. (1985) studied Symptomatic cerebral occlusive disease. Aspirin or aspirin-like drugs vs. Historical control group from the previous year (no drugs) was evaluated on Thrombosis resulting in hemiparesis. Administration of aspirin or aspirin-like drugs prevented thrombosis resulting in hemiparesis following carotid reconstructive surgery compared to historical controls (0 vs 5 patients).
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