Answers are grounded in this paper and cite their sources.
Reaction of 1-benzyl-2,5-dicyanopyrrolidine with alkyl halides give unsymmetrical 2,5-dialkylated products (3) in high yields. Hydrolysis of 3 gives γ-diketones which serve as precursors for jasmone analogues having a cyclopentenone framework, while decyanation and debenzylation of 3 lead to 2,5-dialkylpyrrolidine alkaloids in high yields.
No takes yet. Share an insight, caveat, or question.
Takahashi et al. (1987) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: