Iridium‐Catalyzed Asymmetric Hydrogenation of Quinoline Derivatives with C3*‐TunePhos

A series of C3*‐TunePhos chiral diphosphine ligands has been successfully applied in the iridium‐catalyzed enantioselective hydrogenation of quinolines, and this methodology provided an efficient access to a variety of optically active tetrahydroquinolines with up to 93% ee. Furthermore, attempts on the asymmetric hydrogenation of quinoline N‐oxide are also discussed.