Key result
Decreasing absolute VO2max cut-off values did not significantly predict major postoperative morbidity, but a VO2max less than 35% of predicted was a significant predictor of 90-day survival.
Why the study?
Do decreasing VO2max cut-off values improve risk prediction for postoperative mortality and morbidity in lung cancer surgery candidates?
Cohort (n=119)
No
Do decreasing VO2max cut-off values improve risk prediction for postoperative mortality and morbidity in lung cancer surgery candidates?
Hazard Ratio: 104.08 (95% CI 5.7759–1875.6745)
p-value: p=0.0017
Generalized VO2max cut-off values may not adequately predict major postoperative morbidity in lung cancer surgery candidates, suggesting patient-specific values might be more appropriate.
No takes yet. Share an insight, caveat, or question.
Absolute VO2max thresholds may not reliably predict morbidity after lung cancer surgery; leaves open whether percent-predicted values improve stratification in prospective cohorts.
Rocco et al. (2013) conducted a cohort in Lung cancer surgery candidates (n=119). Decreasing VO2max cut-off values vs. Patients with VO2max above cut-off values was evaluated on 90-day survival (VO2max >35% of predicted) (HR 104.08, 95% CI 5.7759-1875.6745, p=0.0017). Decreasing absolute VO2max cut-off values did not significantly predict major postoperative morbidity, but a VO2max less than 35% of predicted was a significant predictor of 90-day survival.
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