Key result
Self-perceived burden links to poorer quality of life post-mechanical valve replacement, partially mediated by self-care capacity.
Why the study?
The mediating mechanism by which self-perceived burden influences quality of life through self-care capacity remains incompletely understood in patients with mechanical valve replacement.
Cross-Sectional (n=464)
No
Effect estimate: β = -0.165 (95% CI -0.183 to -0.147)
p-value: p=<0.001
Self-care capacity partially mediates the negative impact of self-perceived burden on quality of life in patients following mechanical valve replacement, highlighting a potential target for nursing interventions.
May inform self-care interventions for QoL; hypothesis-generating in cross-sectional data and requires prospective confirmation.
Background Patients undergoing mechanical valve replacement face lifelong physical and psychological challenges that affect quality of life (QoL). While self-perceived burden and self-care capacity are both associated with QoL, the mediating mechanism by which self-perceived burden influences QoL through self-care capacity remains incompletely understood—particularly among patients with mechanical valve replacement. Clarifying this pathway could inform targeted nursing interventions for this population. Aim To examine the mediating role of self-care capacity in the relationship between self-perceived burden and QoL among patients with mechanical valve replacement, using structural equation modeling to evaluate both direct and indirect effects. Methods A cross-sectional design was used with 464 patients from a tertiary hospital in China. Participants completed validated questionnaires: the Self-Perceived Burden Scale(SPBS), the Exercise of Self-Care Agency Scale(ESCAS), and the 36-Item Short Form Survey(SF−36). Self-care capacity was modeled as a mediator within the structural equation modeling framework. Bootstrapping with 5,000 resamples was used to verify the significance of the indirect effect. Results Self-perceived burden was negatively correlated with both self-care capacity( r = −0.760, P < 0.001) and QoL( r = −0.826, P < 0.001). Self-care capacity partially mediated the association between self-perceived burden and QoL (indirect effect: β = −0.165, 95% bootstrap CI : −0.183 to −0.147, P < 0.001). The final model demonstrated good fit( χ 2 /df = 2.742, CFI = 0.969, RMSEA = 0.075). Conclusion Self-care capacity partially mediates the association between self-perceived burden and QoL in patients undergoing mechanical valve replacement. These findings suggest that interventions targeting both burden reduction and self-care enhancement may help improve QoL, though longitudinal and experimental research is needed to establish causal pathways and confirm clinical implications.
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Yang et al. (2026) conducted a cross-sectional in Mechanical valve replacement (n=464). Self-perceived burden was evaluated on Mediating effect of self-care capacity on the relationship between self-perceived burden and quality of life (β = -0.165, 95% CI -0.183 to -0.147, p=<0.001). Self-perceived burden negatively impacted quality of life in patients following mechanical valve replacement, a relationship that was partially mediated by self-care capacity (β = -0.165).
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