Key result
The CURRENT AS Registry-2 enrolled 3,369 patients with severe aortic stenosis, of whom 58% had high-gradient AS and 42% had low-gradient AS, to evaluate contemporary management strategies.
Why the study?
Data evaluating current practice patterns and clinical outcomes for patients with severe aortic stenosis undergoing SAVR, TAVI, or conservative management in the TAVI era are scarce.
Observational (n=3,369)
Yes
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Mortality improved post-TAVR era in severe AS; extends prior registries but leaves open why HF hospitalization rates remained unchanged.
Takeji et al. (2022) conducted an observational in Severe aortic stenosis (n=3,369). Aortic valve replacement (SAVR or TAVI) vs. Conservative management was evaluated on All-cause death, cardiovascular death, and other clinical outcomes (planned). The CURRENT AS Registry-2 enrolled 3,369 patients with severe aortic stenosis, of whom 58% had high-gradient AS and 42% had low-gradient AS, to evaluate contemporary management strategies.
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