Key result
Tissue Doppler imaging and conventional echocardiography were equally effective in detecting diastolic dysfunction (E/A ratio <1.0) in acromegalic patients (49% vs 41%, respectively).
Why the study?
Are conventional echocardiography and tissue Doppler imaging equally effective in demonstrating diastolic dysfunction in acromegalic patients?
Cross-Sectional (n=17)
Are conventional echocardiography and tissue Doppler imaging equally effective in demonstrating diastolic dysfunction in acromegalic patients?
Absolute Event Rate: 49% vs 41%
Conventional echocardiography and tissue Doppler imaging are equally effective in demonstrating diastolic dysfunction, which is a common finding in acromegalic patients.
Findings support method equivalence in acromegaly; hypothesis-generating and should not yet change practice.
UNLABELLED: Acromegaly is associated with myocardial hypertrophy and it can progress to diastolic and systolic dysfunction. PURPOSE: To evaluate diastolic function in acromegalic patients through conventional echocardiography (CD) and tissue Doppler imaging (TDI). METHODS: Seventeen acromegalic patients were submitted to CD and TDI, and early (E) and atriogenic (A) transmitral flow were evaluated in mitral, septal, and tricuspid regions. RESULTS: In comparison with controls the means of conventional (1.06), septal (1.01), and tricuspid (0.98) E/A ratio were significantly lower in acromegalic patients. E/A ratio <1.0 was demonstrated in 41% and 49% of acromegalics by DC and TDI, respectively, with no statistical difference among the two methods. An inverse linear correlation was shown between mitral E/A ratio and acromegalic age (r =-0.7). CONCLUSION: In this study, DC and TDI were equally effective in demonstrating diastolic dysfunction, a common finding in acromegalic patients.
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Leães et al. (2009) conducted a cross-sectional in Acromegaly (n=17). Tissue Doppler imaging (TDI) vs. Conventional echocardiography (CD) was evaluated on E/A ratio <1.0. Tissue Doppler imaging and conventional echocardiography were equally effective in detecting diastolic dysfunction (E/A ratio <1.0) in acromegalic patients (49% vs 41%, respectively).
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