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January 1, 2001Briefings in BioinformaticsOpen Access

Large-scale production of mouse phenotypes: The search for animal models for inherited diseases in humans

Martin Hrabě de Angelis

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Abstract

This paper is aimed principally at bioinformaticians and biologists as an introduction to recent advances in mouse mutagenesis, concentrating on genome-wide screens utilising the powerful mutagen N-ethyl-N-nitroso-urea (ENU). It contains a brief background to the underlying genetics as well as details of the practical aspects of organisation and data capture for such projects.

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Martin Hrabě de Angelis (2001) studied this question.

synapsesocial.com/papers/6a9c8787608b96b680d4e09d https://doi.org/10.1093/bib/2.2.170

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