Key result
Nanoemulsions loaded with nutraceuticals enhanced cell viability by 35-40% compared to doxorubicin alone in H9C2 cardiomyoblasts.
Why the study?
Do nanoemulsions loaded with nutraceuticals protect H9C2 cardiomyoblasts from doxorubicin-induced toxicity?
Population
H9C2 cardiomyoblasts
Comparison
Nanoemulsions loaded with nutraceuticals… vs Doxorubicin alone
Design
Preclinical
Authors
Loading...
May attenuate doxorubicin toxicity in cardiomyoblasts in vitro; leaves open translation to in vivo or clinical settings.
Do nanoemulsions loaded with nutraceuticals protect H9C2 cardiomyoblasts from doxorubicin-induced toxicity?
Nanoemulsions loaded with nutraceuticals, particularly lycopene, protect cardiomyoblasts from doxorubicin-induced cardiotoxicity by reducing inflammation and oxidative stress in vitro.
Quagliariello et al. (2018) studied Doxorubicin-induced cardiotoxicity. Nanoemulsions loaded with nutraceuticals (curcumin and tomato extracts) vs. Doxorubicin alone was evaluated on Cell viability. Nanoemulsions loaded with nutraceuticals enhanced cell viability by 35-40% compared to doxorubicin alone in H9C2 cardiomyoblasts.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: