It is very rare for patients with lung cancer to have metastasis in gastrointestinal tract, especially in the stomach. Herein we describe a 72-year-old male with squamous cell carcinoma of lung. He was referred for whole-body FDG-PET/CT imaging after completion of radiotherapy for suspected of residual tumor and/or local recurrence. The PET images revealed a FDG-avid lesion in the stomach and the co-registered CT images favored a pathological nature rather than physiologic uptake. However, the patient did not complain of abdominal pain or have symptom/sign of upper gastrointestinal (UGI) bleeding. Forty days after the PET/CT study, upper endoscopy was performed due to development of massive UGI bleeding and revealed an ulcerative tumor at the cardiac portion of stomach. Tissue biopsy confirmed a diagnosis of metastatic squamous cell carcinoma identical to previous lung cancer.
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Pai et al. (2010) studied this question.
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