What question did this study set out to answer?

To evaluate the feasibility, safety, and hemostatic impact of the novel ExMeTrA pediatric oxygenator with an integrated pulsatile pump in an animal model.

June 20, 2015ASAIO Journal

First In Vivo Results of a Novel Pediatric Oxygenator with an Integrated Pulsatile Pump

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Authors

KSKatharina StangHeidelberg University RBRalf BorchardtCatholic University of Applied Sciences of North Rhine – Westphalia BNBernd NeumannKainun Institutti

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Implication

Animal study demonstrates stable blood flow and minimal hemostatic activation with a novel pediatric oxygenator in pigs, highlighting its potential for safer neonatal and pediatric support.

Key Points

To evaluate the feasibility, safety, and hemostatic impact of the novel ExMeTrA pediatric oxygenator with an integrated pulsatile pump in an animal model.
Operated the ExMeTrA oxygenator for 6 hours of extracorporeal circulation in a porcine model.
Measured hemodynamic flow parameters along with markers of coagulation, platelet activation, and complement activation.
The integrated pulsatile pump maintained a constant blood flow of 500 mL/min throughout the 6-hour circulation period.
Hemostatic analysis showed only a nonsignificant trend in complement C3 consumption, thrombin-antithrombin-III complex formation, and minimal hemolysis.

Cite This Study

Stang et al. (2015) studied this question.

synapsesocial.com/papers/6a9c97d180b31b2c0d76e65f https://doi.org/10.1097/mat.0000000000000256

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Implication

Animal study demonstrates stable blood flow and minimal hemostatic activation with a novel pediatric oxygenator in pigs, highlighting its potential for safer neonatal and pediatric support.

First In Vivo Results of a Novel Pediatric Oxygenator with an Integrated Pulsatile Pump

Discussion

Member takes

Implication

Key Points

Cite This Study

First In Vivo Results of a Novel Pediatric Oxygenator with an Integrated Pulsatile Pump

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

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