Key result
The standing position induces an anti-gravity stress characterized by systemic vasoconstriction and circulatory insufficiency, eliminating the age-related adaptive components seen in the supine position.
Why the study?
The study was conducted to show the dynamics of the ratio of arterial hypo- and hypercirculation in postnatal ontogenesis.
Does the standing position alter the regulatory setting of arterial circulation compared to the supine position across different age groups?
Cross-Sectional (n=1,944)
Does the standing position alter the regulatory setting of arterial circulation compared to the supine position across different age groups?
The study demonstrates that the gravitational factor in the standing position induces a systemic pressor response and circulatory insufficiency that overrides age-related hemodynamic adaptations observed in the supine position.
Standing assessments may unmask circulatory insufficiency missed supine; leaves open whether gravity overrides age-related adaptations.
The purpose of this study was to show the dynamics of the ratio of arterial hypo- and hypercirculation in postanal ontogenesis. The ratio of opposite hemodynamic phenomena, such as circulatory insufficiency in arterial blood circulation (arterial hypocirculation) and adaptive arterial hypercirculation, reflects the direction of the regulatory setting of the circulatory state of the cardiovascular system. In the regulatory setting of blood circulation in a person in the standing position prevails “anti-gravity stress”, which eliminates the age component detected in the supine position. The defining characteristic of this voltage is the pressor unit for regulating the cardiovascular system, which is characterized by a systemic prevalence of vasoconstriction (hyperresistivity of arterial vessels), as well as signs of circulatory insufficiency. In the supine position, under the conditions of minimal impact of the gravitational factor, adaptive conditions prevail up to 35 years. After 35 years the transition and disadaptive states were registered rottenly. Changes are mainly detected in the standing position in the pelvis-hip and leg block, and after 35 years are fixed in the lying position.
No takes yet. Share an insight, caveat, or question.
Dilenyan et al. (2023) conducted a cross-sectional in Healthy individuals (n=1,944). Standing position (gravitational factor) vs. Supine position was evaluated on Ratio of arterial hypercirculation to arterial hypocirculation (AC1/AC2) (p=<0.01). The standing position induces an anti-gravity stress characterized by systemic vasoconstriction and circulatory insufficiency, eliminating the age-related adaptive components seen in the supine position.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: