Key result
Essential hypertension in CAD patients was associated with a higher incidence of exercise-induced silent myocardial ischemia (60.4% vs 48.8%, P<.05) and higher pain thresholds during pulp testing.
Why the study?
Does essential hypertension reduce pain reactivity and increase silent myocardial ischemia in patients with coronary artery disease?
Observational (n=356)
Does essential hypertension reduce pain reactivity and increase silent myocardial ischemia in patients with coronary artery disease?
Absolute Event Rate: 60.4% vs 48.8%
p-value: p=<.05
Patients with coronary artery disease and essential hypertension exhibit higher pain thresholds and a higher incidence of silent myocardial ischemia compared to normotensive patients.
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Hypertension may mask ischemia symptoms in CAD; hypothesis-generating, prospective studies needed before screening changes.
Falcone et al. (1997) conducted an observational in Coronary artery disease with and without essential hypertension (n=356). Essential hypertension vs. Normotension was evaluated on Incidence of exercise-induced silent myocardial ischemia (p=<.05). Essential hypertension in CAD patients was associated with a higher incidence of exercise-induced silent myocardial ischemia (60.4% vs 48.8%, P<.05) and higher pain thresholds during pulp testing.