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Experimental study demonstrates rapid one-step assembly of dual-modality PSMA probes using a compact MSAP reagent, indicating preserved target affinity with minimal steric hindrance.
We herein reported a novel compact MSAP agent that enables rapid construction of dual-modality PSMA probes via the CBT/1,2-aminothiol click reaction. The design minimizes steric impact and preserves high PSMA affinity.
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Kuo et al. (2025) studied this question.
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