Key result
Left atrial volume independently predicted atrial fibrillation ablation outcome (HR 1.007; 95% CI 1.003-1.011; P=0.001), while pulmonary vein branching pattern had no significant effect.
Why the study?
Does pulmonary vein branching pattern or left atrial volume assessed by MRI predict transcatheter atrial fibrillation ablation outcome?
Cohort (n=330)
Does pulmonary vein branching pattern or left atrial volume assessed by MRI predict transcatheter atrial fibrillation ablation outcome?
Hazard Ratio: 1.007 (95% CI 1.003–1.011)
p-value: p=0.001
Pre-procedural MRI assessment shows that while pulmonary vein branching pattern does not affect AF ablation outcomes, left atrial volume is a strong independent predictor of ablation failure.
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Left atrial volume may aid pre-ablation risk stratification on MRI; observational data leave open prospective validation before guiding patient selection.
Anselmino et al. (2010) conducted a cohort in Atrial fibrillation (n=330). Left atrial volume and pulmonary vein branching pattern was evaluated on Ablation outcome (success defined as AF interruption and/or absence of inducibility) (HR 1.007, 95% CI 1.003-1.011, p=0.001). Left atrial volume independently predicted atrial fibrillation ablation outcome (HR 1.007; 95% CI 1.003-1.011; P=0.001), while pulmonary vein branching pattern had no significant effect.