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The discovery of potentialities of sulfanilamide and its derivatives has been referred to as the greatest therapeutic achievement in modern medicine. Not since Ehrlich's epoch-making discovery of arsphenamine has a remedy of such specificity and utility been offered to world. The literature on clinical and experimental aspects of this group of drugs is enormous. However, several years must elapse before definite indications, proper dosage and methods of administration are determined. It is our purpose to state our opinion concerning value and limitations of sulfanilamide and allied compounds in dermatologic practice, including in addition that of dermatologists from all sections of United States and of many foreign correspondents. 1 Since literature was reviewed recently by Hughes, 2 we have eliminated many references, citing only a few of those not mentioned by this author. The history of development of these drugs and complete study
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Frank C. Combes (1941) studied this question.
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