Key result
Transposition of the great arteries is a serious congenital heart defect with an incidence of 1 in 11,000 births and an 85% mortality rate in the first six months of life.
Population
Patients with transposition of the great arteries
Design
Review
Authors
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High TGA mortality demands prompt diagnosis and intervention; leaves open gaps in pathophysiology for targeted research.
This paper highlights the high mortality of transposition of the great arteries and focuses on its pathophysiology, an area previously underrepresented in the literature.
Noonan et al. (1960) conducted a review in Transposition of the great arteries. Transposition of the great arteries is a serious congenital heart defect with an incidence of 1 in 11,000 births and an 85% mortality rate in the first six months of life.
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