Summary. The lignan identified in human and bovine semen was trans 2,3-bis(3′-hydroxybenzyl)-γ-butyrolactone. It was present in unconjugated and conjugated forms. Mean seminal plasma concentrations were always higher than the corresponding blood plasma levels (between 2·5 and 25 times higher), indicating an efficient clearance capacity of the male reproductive system.
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Dehennin et al. (1982) studied this question.
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