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In the previous publication of this series (2) we described a soluble enzyme system from yeast which catalyzes the biosynthesis of inositol’ from glucose and glucose B-phosphate. The cofactors for this synthesis were shown to be diphosphopyridine nucleotide and Mg+, and when glucose was the substrate ATP was also needed. We have extended these studies, and the present communication presents data on the purification of this system, its properties, and the origin of the carbon atoms of inositol.
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Chen et al. (1965) studied this question.
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