The antioxidant activity of ethyl acetate and methanol extracts of Cantharellus cibarius and Pleurotus porrigens were investigated by using six in vitro assay systems. Mushroom fruit bodies were obtained from the northern region of Iran. Ethyl acetate extracts had higher amounts of phenolic and flavonoids contents than their methanol extracts. Methanol extracts showed higher DPPH scavenging activity than ethyl acetate extracts. C. cibarius ethyl acetate extract showed better reducing powers than others, but was not comparable with vitamin C (P < .001). Methanol extracts exhibited better nitric oxide scavenging activity. The methanol extracts showed very powerful Fe2+ chelating activity. The IC50 values were 16.1 ± 2 for C. cibarius and 21.9 ± 0.9 μg mL−1 for P. porrigens, respectively. There were no significant differences between methanol extracts and EDTA (IC50 = 18 μg mL−1, P < .05). These mushrooms can provide an optimal supply of antioxidant substances in the diet.
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Ebrahimzadeh et al. (2010) studied this question.