The incidence of malignant neoplasms in undescended or ectopic testicles is high. Hinman and Benteen1reported an incidence of 7.5 per cent in cryptorchids and stated that tumors occurred 20 times as frequently in undescended testes as in those normally placed. Pace and Cabot2sectioned 24 testicles removed from the abdomen and detected microscopic evidence of cancer in three. Gilbert and Hamilton3reviewed 7,000 recorded cases of testicular tumors and found 840, or 11 per cent, associated with ectopia, a correlation 48 times higher than expected by chance. Orchiopexy is not necessarily an effective prophylactic measure against the development of malignant degeneration. Gilbert and Hamilton3indicated that 77 tumors occurred in testes previously transferred to the scrotum from an ectopic position. Gilbert4analyzed the cases of 58 of a total of 65 patients (two of his own) reported on in the literature in whom malignant
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Gustave Kaplan (1950) studied this question.