Key result
Electroacupuncture stimulation at Zusanli for 20 minutes attenuated the pressor effect of Ang-(1-7) and the depressor effect of Ang779 in the rostral ventrolateral medulla of anesthetized rats.
Why the study?
Does electroacupuncture attenuate the pressor response to Angiotensin-(1-7) in the rostral ventrolateral medulla of anesthetized rats?
Population
Anesthetized rats
Comparison
Electroacupuncture stimulation at "Zusanli" for… vs Microinjection of Angiotensin- or Ang779 into…
Design
Preclinical
Authors
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Does not inform clinical practice; leaves open whether electroacupuncture modulates central angiotensin effects in humans.
Does electroacupuncture attenuate the pressor response to Angiotensin-(1-7) in the rostral ventrolateral medulla of anesthetized rats?
Electroacupuncture at Zusanli attenuates the pressor effects of Ang-(1-7) in the RVLM of rats, likely by modulating amino acid neurotransmitter release.
Wang et al. (2003) studied this question. Electroacupuncture (EA) stimulation at Zusanli (St.36) was evaluated on Mean arterial pressure (MAP) and amino acid neurotransmitter release. Electroacupuncture stimulation at Zusanli for 20 minutes attenuated the pressor effect of Ang-(1-7) and the depressor effect of Ang779 in the rostral ventrolateral medulla of anesthetized rats.
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