Key result
Twenty-seven monoclonal antibodies detected 17 strains of seven luteoviruses, identifying virus-specific antibodies and common epitopes varying from one to five per virus.
Monoclonal antibodies can discriminate among luteoviruses and identify common epitopes, revealing heterologous reactions.
May enable luteovirus discrimination in plants; leaves open diagnostic validation and broader virology applications.
Twenty-seven monoclonal antibodies to four luteoviruses were tested for their ability to detect 17 strains of seven luteoviruses in triple-antibody-sandwich enzyme-linked immunosorbent assay. Virus-specific monoclonal antibodies were identified for each virus to which antibodies had been produced. Many heterologous reactions, some as strong as the homologous reactions, were detected. The minimum number of epitopes identified on each virus varied from one to five
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Cleora J. D’Arcy (1989) studied Luteoviruses. Monoclonal antibodies was evaluated on Ability to detect strains of luteoviruses in triple-antibody-sandwich enzyme-linked immunosorbent assay. Twenty-seven monoclonal antibodies detected 17 strains of seven luteoviruses, identifying virus-specific antibodies and common epitopes varying from one to five per virus.
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