Key result
Full heparin anticoagulation in acute ischemic stroke is associated with severe bleeding, especially if not closely monitored, despite its ability to reduce erythrocyte-fibrin thrombi development.
Why the study?
Should full heparin anticoagulation be used in acute ischemic stroke?
Should full heparin anticoagulation be used in acute ischemic stroke?
Full heparin anticoagulation is not recommended in acute ischemic stroke due to the risk of severe bleeding.
Heparin reduces development of erythrocyte-fibrin thrombi that form in regions of vascular stasis especially within the heart, in severely stenosed arteries sometimes engrafted on white thrombi, in acute arterial occlusions as fresh tails on existing thrombi, and within extremity and pelvic veins. Unfortunately, heparin use can be associated with severe bleeding, especially if not closely monitored.
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Peter Sandercock (2003) conducted an editorial in Acute Ischemic Stroke. Full Heparin Anticoagulation was evaluated. Full heparin anticoagulation in acute ischemic stroke is associated with severe bleeding, especially if not closely monitored, despite its ability to reduce erythrocyte-fibrin thrombi development.
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