Key result
A final coronary flow velocity reserve of <2.0 after stent implantation predicted a higher need for target lesion revascularization compared to ≥2.0 (22% vs 11%; OR 2.01, 95% CI 1.11-3.66).
Why the study?
Does a final coronary flow velocity reserve < 2.0 predict the need for target lesion revascularization in patients following single vessel stent implantation?
Population
417 patients enrolled in a multicentre prospective randomized study who received a successful single vessel…
Comparison
Final coronary flow velocity reserve < 2.0 vs Final coronary flow velocity reserve >= 2.0
Design
Cohort
Authors
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Post-stent CFR <2.0 was associated with higher TLR; leaves open whether routine measurement improves outcomes.
RCT (n=417)
randomized
Yes
Does a final coronary flow velocity reserve < 2.0 predict the need for target lesion revascularization in patients following single vessel stent implantation?
Odds Ratio: 2.01 (95% CI 1.11–3.66)
Absolute Event Rate: 22% vs 11%
p-value: p=0.010
A final coronary flow velocity reserve of < 2.0 after stent implantation is an independent predictor of the subsequent need for target lesion revascularization.
Toshihiko Nishida (2002) conducted an RCT in Native coronary artery lesions requiring stent implantation (n=417). Final coronary flow velocity reserve < 2.0 vs. Final coronary flow velocity reserve >= 2.0 was evaluated on Target lesion revascularization (OR 2.01, 95% CI 1.11-3.66, p=0.010). A final coronary flow velocity reserve of <2.0 after stent implantation predicted a higher need for target lesion revascularization compared to ≥2.0 (22% vs 11%; OR 2.01, 95% CI 1.11-3.66).
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