Key result
An irreversible restrictive mitral pattern in patients with dilated cardiomyopathy was associated with significantly lower 21-month survival compared to a non-restrictive pattern (34% vs 88%, p=0.0001).
Population
106 patients with dilated cardiomyopathy at a tertiary care centre.
Design
Cohort
Follow-up
21 months
Authors
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May aid risk stratification in dilated cardiomyopathy; leaves open whether restrictive filling is causal or modifiable.
Cohort (n=106)
No
Absolute Event Rate: 34% vs 88%
p-value: p=0.0001
In patients with dilated cardiomyopathy, an irreversible restrictive mitral filling pattern is associated with higher PIIINP levels and significantly worse survival.
Andrea Rossi (2004) conducted a cohort in dilated cardiomyopathy (n=106). irreversible restrictive mitral pattern vs. non-restrictive mitral pattern was evaluated on survival (p=0.0001). An irreversible restrictive mitral pattern in patients with dilated cardiomyopathy was associated with significantly lower 21-month survival compared to a non-restrictive pattern (34% vs 88%, p=0.0001).
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