Assessment of the ability of mice fed on vitamin A supplemented diet to respond to a variety of potential contact sensitizers

This is the authors' abstract. We don't add key points for this paper.

The contact sensitizing potential of various compounds was tested in mice maintained on a diet supplemented with vitamin A acetate. Substances were applied epicutaneously. After challenge, increases in ear thickness were measured and the differences in response between control and treated groups determined by the Mann Whitney test. A number of sensitizers, including Dowicil 200, cinnamaldehyde, hydroxycitronellal and Kathon CG gave positive sensitivity responses.