Key result
Diabetic ESRD patients undergoing maintenance hemodialysis exhibited significantly higher plasma fibrinogen levels (510.81 vs 257.71 mg/dl) and atherogenic index compared to non-diabetic ESRD patients.
Why the study?
Does the presence of diabetes mellitus increase cardiovascular risk markers (lipid profile and fibrinogen) in ESRD patients undergoing haemodialysis compared to non-diabetic ESRD patients?
Cross-Sectional (n=64)
No
Does the presence of diabetes mellitus increase cardiovascular risk markers (lipid profile and fibrinogen) in ESRD patients undergoing haemodialysis compared to non-diabetic ESRD patients?
Diabetic ESRD patients on maintenance haemodialysis exhibit significantly elevated pro-atherogenic lipids and fibrinogen compared to non-diabetics, indicating a higher cardiovascular risk profile.
May signal heightened CV risk in diabetic ESRD on HD; hypothesis-generating, prospective studies needed before practice change.
Background: This study proposes to see whether end stage renal disease (ESRD) patients undergoing haemodialysis with additional diabetes mellitus exhibit increased cardiovascular risk markers in comparison to end stage renal disease (ESRD) patients undergoing haemodialysis without diabetes mellitus.
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A 2018 study conducted a cross-sectional in End Stage Renal Disease (ESRD) undergoing maintenance haemodialysis (n=64). Diabetes mellitus vs. Non-diabetic ESRD patients was evaluated on Plasma fibrinogen level (mg/dl) (p=<0.001). Diabetic ESRD patients undergoing maintenance hemodialysis exhibited significantly higher plasma fibrinogen levels (510.81 vs 257.71 mg/dl) and atherogenic index compared to non-diabetic ESRD patients.
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