Gaia Pellegrini, DDS, PhD/Giulio Rasperini, DDS/Gregory Obot, DDS/Davide Farronato, DDS, PhD, PD, AP/Claudia Dellavia, DDS, PhD: After tooth extraction, 14 alveolar sockets were grafted with porous bovine bone mineral particles and covered with non-cross-linked collagen membrane (test group), and 14 alveolar sockets were left uncovered. At 5 and 12 weeks, microvascular density (MVD), collagen content, and amount of lymphocytes (Lym) T and B were analyzed in soft tissue. At 5 weeks, MVD was significantly lower and Lym T was significantly higher in tests than in controls (P < .05). At 12 weeks no differences were found. Placement of resorbable membrane seems to induce an initial and transient modification of the normal wound healing process of the soft tissue. (Int J Periodontics Restorative Dent 2014;34:531539. doi: 10.11607/prd.1857)
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Pellegrini et al. (2014) studied this question.
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