Key result
Combined preoperative mechanical bowel preparation with oral antibiotics significantly reduces surgical site infection, anastomotic leak, and ileus after colorectal surgery.
Why the study?
Does preoperative mechanical bowel preparation with or without oral antibiotics reduce surgical site infections in patients undergoing colorectal surgery?
Cohort (n=8,442)
Yes
Does preoperative mechanical bowel preparation with or without oral antibiotics reduce surgical site infections in patients undergoing colorectal surgery?
This commentary discusses a cohort study suggesting that combined preoperative mechanical bowel preparation with oral antibiotics may reduce surgical site infections in colorectal surgery.
Commentary on : Kiran RP, Murray AC, Chiuzan C, et al. Combined preoperative mechanical bowel preparation with oral antibiotics significantly reduces surgical site infection, anastomotic leak, and ileus after colorectal surgery. Ann Surg 2015;262:416–25.[OpenUrl][1][CrossRef][2][PubMed][3] The manuscript by Kiran et al 1 investigates a long contentious issue of preoperative bowel preps in colorectal surgery. The authors used the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) 2012 database to compare patients undergoing colon or rectal surgery which received either preoperative mechanical bowel prep alone (MBP+/ABX−), MBP with oral antibiotics (MBP+ABX), or neither MBP or ABX. In total 8442 patients were identified in the cohort. The primary end point of the study was overall surgical site … [1]: {openurl}?query=rft.jtitle%253DAnn%2BSurg%26rft.volume%253D262%26rft.spage%253D416%26rft_id%253Dinfo%253Adoi%252F10.1097%252FSLA.0000000000001416%26rft_id%253Dinfo%253Apmid%252F26258310%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1097/SLA.0000000000001416&link_type=DOI [3]: /lookup/external-ref?access_num=26258310&link_type=MED&atom=%2Febmed%2F21%2F1%2F27.atom
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Christopher R. Mantyh (2015) conducted a cohort in Colorectal surgery (n=8,442). Combined preoperative mechanical bowel preparation with oral antibiotics vs. Mechanical bowel preparation alone or neither mechanical bowel preparation nor oral antibiotics was evaluated on Overall surgical site infection. Combined preoperative mechanical bowel preparation with oral antibiotics significantly reduces surgical site infection, anastomotic leak, and ileus after colorectal surgery.
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