Key result
Fetal hypertrophic cardiomyopathy, normally asymptomatic in utero, can present acutely in type 1 diabetic pregnancies.
Case Report
Highlights the risk and acute presentation of fetal hypertrophic cardiomyopathy in pregnancies complicated by type 1 diabetes.
Alerts clinicians to acute fetal risk in type 1 diabetic pregnancies; hypothesis-generating and requires validation in larger cohorts.
The incidence of intrauterine fetal death in type 1 diabetic patients is significantly higher than in the general population (1). Although vascular disease, poor glycemic control, polyhydramnios, fetal macrosomia, and preeclampsia are associated with a higher incidence of fetal death, the etiology of the increased stillbirth rate remains unknown. Besides other complications, infants of diabetic mothers have long been recognized to be at risk of having hypertrophic cardiomyopathy, a condition that is characterized by thickening of the interventricular septum and ventricular walls, and by systolic and diastolic dysfunction of the neonatal heart. This condition is normally asymptomatic in utero and may only result in congestive heart failure …
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Prefumo et al. (2005) conducted a case report in Fetal Hypertrophic Cardiomyopathy in Type 1 Diabetic Pregnancy. Type 1 Diabetes was evaluated. Fetal hypertrophic cardiomyopathy, normally asymptomatic in utero, can present acutely in type 1 diabetic pregnancies.
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