The Challenges in the Primary Prevention of Osteoarthritis

In the absence of disease-modifying drugs and small to moderate efficacy of symptom relieving therapies, the primary prevention of osteoarthritis (OA) is important. The current review addresses some of the key challenges for primary OA prevention. Identification of the target group, the design of the intervention, and aspects of the effect evaluation are all discussed from an OA prevention perspective. Although OA prevention is still in its infancy, it holds great potential. Given the enormous burden of OA for patients and society, primary OA prevention should be a high priority in the field of OA research.