This review summarizes the evidence, physiologic changes, guideline recommendations, and risks/benefits of antihypertensive medications in older adults.
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Offers clinicians a synthesis of risks, benefits, and guidelines for antihypertensives in older adults; leaves open optimal targets in frail subgroups.
The authors conducted a review of pharmacologic therapy in older adults with hypertension. They reviewed the evidence supporting their use in older adults, understanding the physiologic changes and potential adverse drug effects associated with aging and antihypertensive medication use, exploring guideline recommendations for antihypertensive use in older adults, and evaluating the associated risks and benefits of specific classes of antihypertensive medications.
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Todd et al. (2024) studied this question.
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