Key result
Asymptomatic carotid occlusive disease did not predispose to perioperative stroke, though perioperative mortality was higher in patients with detectable obstruction compared to those without (15.0% vs 3.1%).
Why the study?
Does asymptomatic carotid occlusive disease predispose to perioperative stroke in patients undergoing cardiovascular surgery without prophylactic carotid endarterectomy?
Population
314 patients scheduled for coronary or peripheral arterial reconstruction, screened for asymptomatic carotid…
Comparison
No prophylactic carotid endarterectomy vs Patients without carotid obstruction or bruit
Design
Cohort
Follow-up
perioperative
Authors
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Does not support routine prophylactic endarterectomy; leaves open whether obstruction drives excess perioperative mortality.
Cohort (n=314)
Does asymptomatic carotid occlusive disease predispose to perioperative stroke in patients undergoing cardiovascular surgery without prophylactic carotid endarterectomy?
Absolute Event Rate: 15% vs 3.1%
Asymptomatic carotid occlusive disease does not necessarily predispose to perioperative stroke during cardiovascular surgery, suggesting prophylactic carotid endarterectomy may not be necessary.
Barnes et al. (1981) conducted a cohort in Cardiovascular surgical patients (coronary or peripheral arterial reconstruction) (n=314). Asymptomatic carotid occlusive disease vs. No carotid obstruction was evaluated on Perioperative mortality. Asymptomatic carotid occlusive disease did not predispose to perioperative stroke, though perioperative mortality was higher in patients with detectable obstruction compared to those without (15.0% vs 3.1%).
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