Key result
Morphine sulphate administration in patients with uncomplicated myocardial infarction showed a slight tendency to cause orthostatic hypotension, with no marked fall in cardiac output.
Why the study?
Does morphine affect blood pressure and cardiac output in patients with uncomplicated acute myocardial infarction?
Population
25 patients with uncomplicated acute myocardial infarction
Comparison
Morphine sulphate vs Placebo injection
Design
RCT, Double blind
Authors
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May prompt orthostatic monitoring with morphine in uncomplicated MI; confirms preserved cardiac output in this RCT.
RCT (n=20)
Double-blind
Does morphine affect blood pressure and cardiac output in patients with uncomplicated acute myocardial infarction?
Morphine administration in uncomplicated myocardial infarction causes a slight tendency toward orthostatic hypotension without a marked fall in cardiac output.
Grendahl et al. (1969) conducted an RCT in uncomplicated myocardial infarction (n=20). Morphine sulphate vs. Placebo was evaluated on Blood pressure and cardiac output. Morphine sulphate administration in patients with uncomplicated myocardial infarction showed a slight tendency to cause orthostatic hypotension, with no marked fall in cardiac output.
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