Key result
Treatment with intravenous insulin and gemfibrozil safely and effectively reduced serum triglyceride levels and resolved symptoms in a patient with hypertriglyceridemia-induced acute pancreatitis.
Case Report (n=1)
No
This case highlights hypertriglyceridemia as a rare cause of acute pancreatitis that can be treated with medical management without plasmapheresis.
May support plasmapheresis avoidance via insulin-gemfibrozil; leaves open confirmation in prospective cohorts.
Hypertriglyceridemia is third prevailing cause of acute pancreatitis after biliary and alcoholic etiology. It accounts for 1 to 4% cases of pancreatitis. Present case describes a thirty years old diabetic male, who presented in emergency with pain in the abdomen and yellow discoloration of the skin. He was admitted with suspicion of diabetic ketoacidosis (DKA), but no improvement was seen after DKA treatment. His laboratory investigations showed normal serum amylase levels and dyslipidemia with raised serum triglycerides levels. He was diagnosed as acute pancreatitis secondary to hypertriglyceridemia, which is considered as a rare cause of acute pancreatitis.
No takes yet. Share an insight, caveat, or question.
Naveed et al. (2021) conducted a case report in Hypertriglyceridemia-induced acute pancreatitis (n=1). Intravenous insulin and gemfibrozil was evaluated on Clinical recovery and reduction in serum triglycerides. Treatment with intravenous insulin and gemfibrozil safely and effectively reduced serum triglyceride levels and resolved symptoms in a patient with hypertriglyceridemia-induced acute pancreatitis.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: