Key result
IV insulin, fenofibrate, and icosapent ethyl resolve HTG-induced pancreatitis and DKA, cutting triglycerides ~89%.
Why the study?
Hypertriglyceridemia-induced pancreatitis is rare but can cause severe disease, and its co-existence with diabetic ketoacidosis complicates diagnosis and management.
Population
47-year-old male with epigastric pain diagnosed with hypertriglyceridemia-induced pancreatitis and DKA
Design
Case report
Authors
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May support multimodal therapy in overlapping hypertriglyceridemia pancreatitis and DKA; hypothesis-generating and requires prospective validation.
Case Report (n=1)
Highlights the rare and potentially overlapping clinical presentation of hypertriglyceridemia-induced pancreatitis and diabetic ketoacidosis, emphasizing the need for timely diagnosis.
Naqvi et al. (2021) conducted a case report in Hypertriglyceridemia-induced pancreatitis and diabetic ketoacidosis (n=1). Intravenous insulin, fenofibrate, and icosapent ethyl was evaluated on Triglyceride levels and clinical symptoms. Treatment with intravenous insulin, fenofibrate, and icosapent ethyl successfully resolved concurrent hypertriglyceridemia-induced pancreatitis and diabetic ketoacidosis, lowering triglycerides from 8075 mg/dL to 866 mg/dL.
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