Key result
Prompt hydration, insulin, and plasmapheresis resolve the rare triad of severe hypertriglyceridemia, pancreatitis, and DKA.
Why the study?
The coexistence of diabetic ketoacidosis and acute pancreatitis in the presence of hypertriglyceridemia is rare and presents diagnostic and therapeutic challenges.
Population
42-year-old female with poorly controlled type 2 diabetes mellitus
Design
Case report
Authors
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Single-case success warrants caution before routine plasmapheresis adoption; leaves open its role in hypertriglyceridemic pancreatitis with DKA.
Case Report (n=1)
Highlights the rare coexistence of diabetic ketoacidosis and acute pancreatitis in the presence of hypertriglyceridemia and the need for tailored management.
Oshikoya et al. (2023) conducted a case report in Hypertriglyceridemia-induced acute pancreatitis complicated by diabetic ketoacidosis (n=1). Insulin infusion and plasmapheresis was evaluated on Clinical recovery and normalization of serum triglyceride, lipase, and amylase levels. Prompt management with intravenous hydration, insulin infusion, and plasmapheresis led to the successful clinical recovery of a 42-year-old female presenting with the rare triad of hypertriglyceridemia-induced acute pancreatitis and diabetic ketoacidosis.
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