Key result
Acute pancreatitis can complicate diabetic ketoacidosis despite only mild hypertriglyceridemia under 200 mg/dL.
Why the study?
The triad of acute pancreatitis, diabetic ketoacidosis, and hypertriglyceridemia is rare and not fully understood, especially in cases with mild hypertriglyceridemia.
Case Report (n=2)
No
Highlights that acute pancreatitis can occur in diabetic ketoacidosis even with mild hypertriglyceridemia (TG < 200 mg/dL), contrary to the typical association with severe hypertriglyceridemia.
Answers are grounded in this paper and cite their sources.
Acute pancreatitis may complicate DKA even with mild hypertriglyceridemia; case reports leave open incidence and causality.
Hypertriglyceridemia (HTG) is a well-established cause of acute pancreatitis (AP). Diabetic ketoacidosis (DKA) leads to lipolysis and HTG, and can result in AP. Triad of AP, DKA, and HTG is rare and not fully understood. Usually AP is associated with severe HTG with serum triglyceride (TG) level over 1,000 mg/dL. However, we experienced two cases of AP in DKA with mild HTG with TG level less than 200 mg/dL. Herein, we report these unusual cases and provide a review of the literature about the triad of DKA, HTG, and AP.
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Cho et al. (2021) conducted a case report in Diabetic ketoacidosis and acute pancreatitis (n=2). Diabetic ketoacidosis with mild hypertriglyceridemia was evaluated. Acute pancreatitis can occur in patients with diabetic ketoacidosis who have only mild hypertriglyceridemia (triglycerides <200 mg/dL), with both cases recovering after hydration and insulin.
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