Research Progress on Pathogenesis of Melasma

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Melasma is a common facial symmetrical pigmentation skin disease, which occurs in women of childbearing age and seriously affects the appearance and quality of life of female patients.At present, the etiology and pathogenesis of melasma have not been fully elucidated.In recent years, many studies have shown that ultraviolet radiation, hormone levels, genetic factors, inflammatory reactions, free radicals and skin microbial factors play an important role in the pathogenesis of melasma.This article reviews the research progress of the pathogenesis of melasma in order to better prevent and treat melasma in clinic.