Key result
Preclinical DNA diagnosis using polymorphous markers and SMN gene deletion analysis successfully identified presymptomatic proximal spinal muscle atrophy in a family.
Answers are grounded in this paper and cite their sources.
DNA-study is suggested for all members of families in which patients with spinal muscle atrophy are revealed.
Case of preclinical DNA-diagnosis in a family with the use of polymorphous markers in the region 5gll.2-gl3.3 and search of the SMN gene deletion is presented. It has been suggested to perform DNA-study in all the members of families in which patients with spinal muscle atrophy were revealed.
No takes yet. Share an insight, caveat, or question.
Yudina et al. (1997) studied this question. Preclinical DNA diagnosis using polymorphous markers and SMN gene deletion analysis successfully identified presymptomatic proximal spinal muscle atrophy in a family.
Synapse has enriched 10 related papers. Consider them for comparative context: