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Narrative review demonstrates the regenerative efficacy of nano fat grafting in facial rejuvenation, highlighting stem cell advantages over conventional hyaluronic acid skin boosters.
Facial rejuvenation has progressively shifted from volumetric correction toward biologically driven regenerative therapies. Autologous fat grafting has gained prominence due to its ability to restore both volume and tissue quality. Among its various forms, nano fat grafting has emerged as a purely regenerative technique, characterized by a high concentration of stromal vascular fraction and adipose‐derived stem cells with minimal viable adipocytes. This article review discusses the biological basis, preparation techniques, clinical indications, and outcomes of nano fat grafting in facial rejuvenation. A comparison has been done between nano Fat grafting and injectable, hyaluronic, skin, boosters, and also emphasis has been taken on the importance of optimal donor [1–4].
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Rao et al. (2026) studied this question.
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