Key result
Gastroesophageal reflux disease was associated with a significantly higher prevalence of severe autonomic dysfunction compared to healthy controls (44.4% vs 7.9%, p<0.001).
Why the study?
Do patients with gastroesophageal reflux disease have impaired cardiac autonomic function compared to healthy controls?
Population
145 participants, including 29 patients with a diagnosis of gastroesophageal reflux disease and 116 age- and…
Design
Case-control
Authors
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GERD patients exhibit vagal impairment on HRV testing; leaves open whether autonomic assessment should inform management.
Observational (n=145)
No
Do patients with gastroesophageal reflux disease have impaired cardiac autonomic function compared to healthy controls?
Absolute Event Rate: 44.4% vs 7.9%
p-value: p=<0.001
Patients with GERD exhibit significant cardiac autonomic dysfunction, particularly impaired parasympathetic function, compared to healthy controls.
Milovanović et al. (2015) conducted an observational in Gastroesophageal reflux disease (GERD) (n=145). Gastroesophageal reflux disease vs. Healthy volunteers was evaluated on Severe autonomic dysfunction (p=<0.001). Gastroesophageal reflux disease was associated with a significantly higher prevalence of severe autonomic dysfunction compared to healthy controls (44.4% vs 7.9%, p<0.001).
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