Key result
Vertical sleeve gastrectomy demonstrated remission of diabetes in up to 60% of patients after one year, though differences compared to clinical management were not observed after three years.
Why the study?
Does vertical sleeve gastrectomy improve weight loss and glycemic control in obese patients with type 2 diabetes?
Does vertical sleeve gastrectomy improve weight loss and glycemic control in obese patients with type 2 diabetes?
Vertical sleeve gastrectomy promotes short-term weight loss and diabetes remission, but its long-term durability compared to clinical management remains uncertain.
VSG mechanisms in obesity and diabetes extend physiological insights; leaves open need for prospective validation before practice change.
BACKGROUND: Currently, bariatric surgery has promoted weight loss and improved glycemic control in obese patients through different techniques, including vertical sleeve gastrectomy. AIM: Present and update the different vertical sleeve gastrectomy ways of action, both in the treatment of obesity and diabetes, approaching its potential effect on gastrointestinal physiology, as well as the benefits achieved by this manipulation. METHODS: Pubmed database search was used crossing the headings: obesity, type 2 diabetes and sleeve gastrectomy. RESULTS: Published data have shown that short-term weight loss tends to be higher in patients undergoing vertical sleeve gastrectomy compared to Roux-en-Y gastric bypass. In relation to glycemic control, the procedure demonstrated remission of diabetes in up to 60% after one year of surgery. After three years, however, differences in remission rate between surgical and clinical group was not observed, questioning the durability of the technical in a long-term. CONCLUSION: Despite showing good results, both in the weight loss and co-morbidities, conflicting results reinforce the need for more studies to prove the efficiency of the vertical sleeve gastrectomy as well as to understand its action about the molecular mechanisms involved in the disease.
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Fuchs et al. (2017) conducted a review in Obesity and type 2 diabetes. Vertical sleeve gastrectomy vs. Roux-en-Y gastric bypass and clinical management was evaluated on Remission of diabetes. Vertical sleeve gastrectomy demonstrated remission of diabetes in up to 60% of patients after one year, though differences compared to clinical management were not observed after three years.
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