Key result
Stereotactic body radiation therapy reduced ventricular tachycardia episodes from 189 per 24 hours to 0 in a patient with an unresectable cardiac lipoma.
Why the study?
Does stereotactic body radiation therapy reduce ventricular tachycardia episodes in a patient with refractory VT secondary to cardiac lipoma?
Case Report (n=1)
Does stereotactic body radiation therapy reduce ventricular tachycardia episodes in a patient with refractory VT secondary to cardiac lipoma?
Absolute Event Rate: 0% vs 189%
Stereotactic body radiation therapy (SBRT) may be a viable and effective treatment option for patients with cardiac tumors who develop refractory ventricular arrhythmias unresponsive to conventional therapies.
SBRT may reduce VT burden in refractory unresectable cardiac lipoma; hypothesis-generating and requires prospective validation.
We present the case of a 29-year-old man who developed ventricular tachycardia (VT) secondary to a cardiac lipoma located adjacent to the interventricular groove, which could not be fully resected. Antiarrhythmic drugs and endocardial and epicardial ablation failed to prevent VT recurrence. Finally, noninvasive stereotactic body radiation therapy (SBRT) targeting the lipoma was performed, with a total dose of 24 Gy delivered in three fractions. The number of VT episodes was reduced from 189/24 h before SBRT to 0 after the procedure. At 4-month follow-up, there were no signs of therapy-related complications. Our experience suggests that SBRT could emerge as a viable treatment option for patients with cardiac tumors who develop refractory ventricular arrhythmias.
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Zeng et al. (2019) conducted a case report in Refractory ventricular tachycardia secondary to cardiac lipoma (n=1). Stereotactic body radiation therapy (SBRT) was evaluated on Number of VT episodes per 24 h. Stereotactic body radiation therapy reduced ventricular tachycardia episodes from 189 per 24 hours to 0 in a patient with an unresectable cardiac lipoma.
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