What is the clinical evidence from this study?

Study design: Other. Population: Myotonic dystrophy.

January 1, 1995Human Molecular Genetics

A novel homeodomain-encoding gene is associated with a large CpG island interrupted by the myotonic dystrophy unstable (CTG)n repeat

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Key result

Sequencing of the myotonic dystrophy region identified a novel homeodomain-encoding gene (DMAHP) associated with a 3.5 kb CpG island interrupted by the (CTG)n repeat, expressed in multiple tissues.

Authors

CBCatherine BoucherUniversité Laval SKStephanie KingCleveland Clinic NCNessa CareyUniversity of Leicester

Discussion

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Implication

Does not change myotonic dystrophy management; leaves open DMAHP's causal role pending functional studies.

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Population

Myotonic dystrophy

Cite This Study

Boucher et al. (1995) studied Myotonic dystrophy. Sequencing of the myotonic dystrophy region identified a novel homeodomain-encoding gene (DMAHP) associated with a 3.5 kb CpG island interrupted by the (CTG)n repeat, expressed in multiple tissues.

synapsesocial.com/papers/6a9d42347ce56dd70348a689 https://doi.org/10.1093/hmg/4.10.1919

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A novel homeodomain-encoding gene is associated with a large CpG island interrupted by the myotonic dystrophy unstable (CTG)n repeat

Discussion

Member takes

Implication

PICO

Cite This Study

A novel homeodomain-encoding gene is associated with a large CpG island interrupted by the myotonic dystrophy unstable (CTG)n repeat

Discussion

Member takes

Implication

PICO

Cite This Study

Also Consider

Also Consider